Tap water is an adequate cleansant for minor wounds

Date First Published:
March 1, 2000
Last Updated:
November 8, 2003
Report by:
Sandy Thompson, Medical Student (Manchester Royal Infirmary)
Search checked by:
Fiona Lecky, Manchester Royal Infirmary
Three-Part Question:
In [patients with lacerations] is [wound toilet with iodine solution or sterile saline more effective than wound toilet with tap water] at [reducing rate of infection]?
Clinical Scenario:
A patient presents to the Emergency Department with a laceration to the right forearm. The wound will need cleaning and then closing. There appear to be many different cleaning solutions available - you wonder which is best.
Search Strategy:
Medline 1966-10/03 using the OVID interface on ATHENS (including Medline in progress and non-indexed citations)
Search Details:
({[exp "wounds and injuries" OR exp wounds, penetrating OR laceration$.ti,ab,rw,sh OR wound$.ti,ab,rw,sh OR cut$.ti,ab,rw,sh] AND [exp iodine OR exp iodine compounds OR exp povidone-iodine OR iodine$.ti,ab,rw,sh OR exp sodium chloride OR saline.ti,ab,rw,sh OR anti-infective agents, local OR antiseptic$.ti,ab,rw,sh] AND [clean$.ti,ab,rw,sh OR exp decontamination OR exp sterilisation OR exp disinfection OR decontaminate$.ti,ab,rw,sh OR exp irrigation OR lavage.ti,ab,rw,sh]} AND [random$.af] LIMIT to human and english and abstracts)
Outcome:
397 papers found. One citation is a cochrane review of tap water use. There are no individual published after the cochrane review. 4 other papers not included in the cochrane review of water are also included.
Relevant Paper(s):
Study Title Patient Group Study type (level of evidence) Outcomes Key results Study Weaknesses
water for wound cleaning fernandez r; griffiths t; ussia c 2001 (updated April 2003) Australia A variety of patients were included in the review. 5 of the 6 trials included in the review used emergency department patients. Meta-analysis of trials of wound cleansing. tap water vs normal saline (2 trials) - infection rates OR 0.52 (CI 0.28 - 0.96) in favour of tap water Only 6 trials were included in this well conducted review. There were concerns regarding the methodological quality of several of the included trials. No trials included children.
distilled water or cool boiled water vs normal saline (1 trial) - infection rates OR 0.55 (CI 0.18-1.6s NS) in favour of tap water
A prospective trial of prophylactic povidone iodine in lacerations of the hand Roberts AH, Roberts FE, Hall RI, Thomas IH 1985 UK 418 patients with hand lacerations.
All wounds cleaned with savlodil. Experimental group sprayed with povidone-iodine
Randomised clinical trial. Infection rate 4.6% (povidone-iodine) vs 5.3% (control) (NS) Poor randomisation.
No control.
96 lost to follow up.
Imperfect healing 35.5% (povidone-iodine) vs 41.2% (control) (NS)
A trial of povidone-iodine in the prevention of infection in sutured lacerations. Gravett A, Sterner S, Clinton JE, Ruiz E. 1987 USA. 500 emergency department patients with lacerations requiring sutures.
All wounds irrigated with normal saline. Experimental group irrigated and scrubbed with 1% povidone iodine.
Randomised clinical trial. Infection rate 15.4% (control) vs 5.47% (povidone-iodine) No control.
105 patients lost to follow up and 122 followed up by phone only.
High control infection rate.
A comparison of wound irrigation solutions used in the emergency department. Dire DJ, Welsh AP. 1990 USA. 531 patients with minor, uncomplicated soft-tissue lacerations requiring suturing.
Treated with either irrigation with normal saline, 1% povidone-iodine or F-68 (Shur-Clens).
Clinical trial Infection rates 6.9% (normal saline) vs 4.3% (povidone-iodine) vs 5.6% (F-68). Non significant Not randomised.
Effect of povidone-iodine and saline soaking on bacterial counts in acute, traumatic, contaminated wounds. Lammers RL, Fourre M, Callaham ML, Boone T. 1990 USA 35 patients with 37 heavily contaminated wounds requiring debridement.
Randomised to soaking for 10 min with either 1% povidone-iodine solution, normal saline or covering for 10 min with a dry dressing.
PRCT Change in bacterial counts No change povidone-iodine group or control. Increase in saline group Small numbers.
Author Commentary:
It is striking that the infection rate remains 5 - 10% whatever the intervention. In this case the cheapest and most easily obtained solution should be used. The meta-analysis shows that tap water may have a beneficial effect.

Clearly the quality of water should be good (at least potable)
Bottom Line:
Tap water is a safe and effective solution for cleaning recent wounds requiring closure and is the treatment of choice.
Level of Evidence:
Level 1: Recent well-done systematic review was considered or a study of high quality is available
References:
  1. fernandez r; griffiths t; ussia c. water for wound cleaning
  2. Roberts AH, Roberts FE, Hall RI, Thomas IH. A prospective trial of prophylactic povidone iodine in lacerations of the hand
  3. Gravett A, Sterner S, Clinton JE, Ruiz E.. A trial of povidone-iodine in the prevention of infection in sutured lacerations.
  4. Dire DJ, Welsh AP.. A comparison of wound irrigation solutions used in the emergency department.
  5. Lammers RL, Fourre M, Callaham ML, Boone T.. Effect of povidone-iodine and saline soaking on bacterial counts in acute, traumatic, contaminated wounds.