Lateral ligament ankle sprains should be mobilised early

Date First Published:
March 1, 2000
Last Updated:
April 11, 2001
Report by:
Gordon Higgins, Medical Student (Manchester Royal Infirmary)
Search checked by:
Bruce Martin, Manchester Royal Infirmary
Three-Part Question:
In [adults with lateral ligament ankle sprains] is [immediate mobilisation better than immobilisation in a cast] at [decreasing pain and reducing time to full recovery].
Clinical Scenario:
A 28 year old man presents to the emergency department with a swollen, bruised and painful ankle following an inversion injury. After examination and appropriate investigations a grade 2 inversion ankle sprain is diagnosed. You wonder whether early mobilisation or immobilisation in a short leg cast is more suitable for this patient.
Search Strategy:
Medline 1966-12/98 using the OVID interface.
Search Details:
[{exp ankle OR ankle$.mp OR exp ankle injuries OR exp ankle joint OR exp lateral ligament, ankle} AND {exp sprains and strains OR sprain$.mp} AND {mobilis$.mp OR mobilisation$.mp OR mobilization$.mp}] LIMIT to human and english language.
Outcome:
20 papers found of which 15 were irrelevant to the study question or of insufficient quality for inclusion.
Relevant Paper(s):
Study Title Patient Group Study type (level of evidence) Outcomes Key results Study Weaknesses
Ann Emerg Med Hedges JR, Anwar RA. Management of ankle sprains. 1980 UK 93 patients aged 15-65 with ankle sprains
Elastic bandage and early weight bearing vs non-weight bearing plaster splint
Followed at 1 week and 8 months
PRCT Functional disability No significant difference Many patients had previous injuries. 8 month follow-up in only 33%.
Pain No significant difference
Swelling No significant difference
Recurrent injury No significant difference
Early ankle mobilisation, Pt 1: The immediate effect on acute, lateral ankle sprains. Dettori JR, Basmania CJ, Pearson BD et al. 1994 USA 64 military personnel with ankle sprains
Plaster cast vs air-stirrup vs elastic wrap for 2 weeks
Followed during early course2 and at 1 year3
PRCT Return to work and running Quicker with early mobilisation (P=0.029) Moderate and severe sprains only. Long term follow-up by postal questionnaire
Range of motion Significantly more with early mobilisation
Swelling and pain Significantly less with early mobilisation
Difficulty running at 1 year No significant difference
Early mobilization versus immobilization in the treatment of lateral ankle sprains. Eiff MP, Smith AT, Smith GE. 1994 USA 82 military personnel with ankle sprains
Elastic wrap for 2 days followed by air stirrup for 8 days vs non weight-bearing splint for 10 days
Followed up at 3 and 6 weeks and 6 and 12 months
PRCT Return to work Significantly more likely in elastic wrap group
Pain Less pain (P=0.02) at 3 weeks in elastic wrap group
Residual symptoms No significant difference
Treatment modalities for soft tissue injuries of the ankle: a critical review. Ogilvie-Harris DJ, Gilbart M. 1995 Canada 84 articles on soft tissue ankle injuries Critical review Functional outcome Early mobilisation appears to be better No formal meta-analysis. Not all studies directly relevant to the study question.
Treatment of lateral collateral ligament sprains of the ankle: a critical appraisal of the literature. Shrier I. 1995 Canada 13 RCTs on ankle sprains Critical appraisal Pain Less with early mobilisation No formal meta-analysis. Not all studies directly relevant to the study question.
Swelling Less with early mobilisation
Instability Less with early mobilisation
Author Commentary:
While many papers have addressed the question there are few relevant RCTs. The two relevant reviews do not address the question directly and do not attempt formal meta-analysis.
Bottom Line:
Early mobilisation of ankle sprains leads to quicker short term recovery without affecting long term outcome. It is the treatment of choice.
References:
  1. Hedges JR, Anwar RA. Management of ankle sprains.. Ann Emerg Med
  2. Dettori JR, Basmania CJ, Pearson BD et al.. Early ankle mobilisation, Pt 1: The immediate effect on acute, lateral ankle sprains.
  3. Eiff MP, Smith AT, Smith GE.. Early mobilization versus immobilization in the treatment of lateral ankle sprains.
  4. Ogilvie-Harris DJ, Gilbart M.. Treatment modalities for soft tissue injuries of the ankle: a critical review.
  5. Shrier I.. Treatment of lateral collateral ligament sprains of the ankle: a critical appraisal of the literature.