Eye patches are not indicated for simple corneal abrasions

Date First Published:
March 1, 2000
Last Updated:
April 11, 2001
Report by:
Kevin Mackway-Jones, Consultant (Manchester Royal Infirmary)
Search checked by:
Simon Carley, Manchester Royal Infirmary
Three-Part Question:
In [patients with superficial corneal abrasions] is [an eye patch better than no eye patch] at reducing [pain and time to healing]
Clinical Scenario:
A young woman attends the Emergency Department with pain in her right eye. Her infant son has inadvertently put his hand in her eye. Examination reveals a corneal abrasion. You wonder whether an eye patch should be applied to protect the cornea.
Search Strategy:
Medline 1966-12/98 using the OVID interface.
Search Details:
{[exp eye injuries OR exp eye foreign bodies OR corneal abrasion$.mp] AND [exp bandages OR eye patch$.mp OR patch$.mp]} AND [maximally sensitive RCT filter].
Outcome:
41 papers found of which 28 irrelevant and 4 of insufficient quality for inclusion
Relevant Paper(s):
Study Title Patient Group Study type (level of evidence) Outcomes Key results Study Weaknesses
Efficacy of eyepad in corneal healing after corneal foreign body removal. Hulbert MF. 1991 UK 30 patients with corneal abrasion after foreign body removal
Chloramphenicol and eye patch vs chloramphenicol alone
PRCT Discomfort Greater at 24h
Time to healing No difference
No eye pad for corneal abrasion. Kirkpatrick JN, Hoh HB, Cook SD. 1993 UK ** patients with simple traumatic corneal abrasions
Antibiotic, mydriatic and eye patch vs antibiotic and mydriatic alone
PRCT Time to healing Significantly <0.05) better in antibiotic alone group
Eye patch treatment for the pain of corneal abrasion. Patterson J, Fetzer D, Krall J et al. 1996 USA 33 patients with eye pain and corneal abrasion
Eye patch vs no eye patch
PRCT Pain score No difference Small study - low power
Analgesic use No difference
A comparison of pressure patching versus no patching for corneal abrasions due to trauma or foreign body removal. Kaiser PK. 1997 USA 201 patients with non-infected non contact lens related traumatic (120) or post foreign body removal (81) corneal abrasions.
Antibiotic, mydriatic and eye patch vs antibiotic and mydriatic alone
PRCT Pain Significantly less in antibiotic/mydriatic alone group
Time to healing Significantly less in antibiotic/mydriatic alone group
Blurred vision Significantly less in antibiotic/mydriatic alone group for traumatic abrasions, no difference for abrasions post foreign body removal.
The evaluation of eye patching in the treatment of traumatic corneal epithelial defects. Campanile TM, St Clair DA, Benaim M. 1997 USA 64 patients with traumatic corneal abrasion
Patched vs unpatched
PRCT Rate of healing at day 1 Significantly faster in unpatched Only recorded at 1 day
The management of corneal abrasions in accident and emergency. Hart A, White S, Conboy P et al. 1997 UK 99 patients with corneal abrasion
Eye pad vs no eye pad
Controlled trial Duration of pain No significant difference
Should we patch corneal erosions? Arbour JD, Brunette I, Boisjoly HM et al. 1997 Canada 48 eyes (46 patients) with corneal erosion
Patching vs no patching
PRCT Linear and surface speed of reepithelialisation No significant difference
Pain No significant difference
Insomnia No significant difference
Author Commentary:
There are 6 PRCTs of varying quality and power in this area. All show no benefit from patching and the largest shows positive benefit from no patch.
Bottom Line:
Patients with corneal abrasion should not have an eye patch.
References:
  1. Hulbert MF.. Efficacy of eyepad in corneal healing after corneal foreign body removal.
  2. Kirkpatrick JN, Hoh HB, Cook SD.. No eye pad for corneal abrasion.
  3. Patterson J, Fetzer D, Krall J et al.. Eye patch treatment for the pain of corneal abrasion.
  4. Kaiser PK.. A comparison of pressure patching versus no patching for corneal abrasions due to trauma or foreign body removal.
  5. Campanile TM, St Clair DA, Benaim M.. The evaluation of eye patching in the treatment of traumatic corneal epithelial defects.
  6. Hart A, White S, Conboy P et al.. The management of corneal abrasions in accident and emergency.
  7. Arbour JD, Brunette I, Boisjoly HM et al.. Should we patch corneal erosions?