Naloxone Titration vs Bolus doses in acute opioid overdose

Date First Published:

October 29, 2020

Last Updated:

October 29, 2020

Report by:

Oliver Hobbs, Specialist Paramedic (Manchester Metropolitan University )

Three-Part Question:

[In adults presenting with acute opioid overdose in the prehospital setting] does [titration of Naloxone in quantities to reverse respiratory and cardiovascular depression whilst maintained reduced GCS as opposed to regular bolus doses] [reduce acute withdrawal and mortality]