Best evidence topic report: Does Baseline Serum Lactate Predict Outcomes in Diabetic Ketoacidosis Patients?
Date First Published:
January 27, 2025
Last Updated:
January 27, 2025
Report by:
Mostafa Alavi-Moghaddam, Full Professor of Medical School Department of Emergency Medicine (Emergency Medicine Department, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran)
Search checked by:
Ramin Zeinodini, Emergency Medicine Department, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Three-Part Question:
In [patients with diabetic ketoacidosis (DKA)], does [a higher baseline serum lactate level compared to a lower level] predict [worse outcomes, such as increased hospital or intensive care unit length of stay, morbidity, and mortality]?
Relevant Paper(s):
| Study Title | Patient Group | Study type (level of evidence) | Outcomes | Key results | Study Weaknesses |
|---|---|---|---|---|---|
| Deciphering the role of lactate as a prognostic indicator in pediatric diabetic ketoacidosis Ozel 2024 Turkey | DKA resolution time Pediatric ICU LOS | Correlation of serum lactate with: •tDKA resolution time: p=0.746, r=0.031 •tPICU LOS: p=0.109, r=0.152 |
References:
- Ozel. Deciphering the role of lactate as a prognostic indicator in pediatric diabetic ketoacidosis