Clinical tests for Scaphoid fractures

Date First Published:
September 21, 2008
Last Updated:
April 7, 2011
Report by:
Michael Callaghan , ESP (Manchester Royal infirmary)
Search checked by:
Janet Fowler, Manchester Royal infirmary
Three-Part Question:
In [adults with suspected scaphoid fracture] which [is the best clinical test] to [diagnose this injury]
Clinical Scenario:
A 41 year old female presents to the department hours after a FOOSH. She has pain on the radial side of the wrist and over the ASB. You wonder if she has had a fracture of the scaphoid and want to know the best clinical test to help the diagnosis
Search Strategy:
MEDLINE 1966-2/11, CINAHL 1982 2/11, AMED 1985-2/11, SPORTDiscus 1830-2/11, EMBASE 1996-2/11, via the OVID interface. The Cochrane database, December 2009 and PEDro database, December 2009.
Search Details:
Medline, CINAHL, AMED, EMBASE, SPORTSDiscus, Cochrane database: [{(exp scaphoid bone OR exp carpal navicular bone OR scaphoid.mp) AND (fracture.mp) AND (examin$mp OR clinical test.mp)]
LIMIT to human AND English language AND diagnostic sensitivity and specificity.
Outcome:
198 papers were retrieved, of which 6 were relevant to the 3 part question. 1 used MR imaging as the reference test and the other 4 used plain radiography, and 1 used a combination of plain radiography and scintigraphy.
Relevant Paper(s):
Study Title Patient Group Study type (level of evidence) Outcomes Key results Study Weaknesses
A prospective study identifying the sensitivity of radiographic findings and the efficacy of clinical findings in carpal navicular fractures. Waeckerle JF 1987, USA N = 85
Reference standard: Plain radiograph
Diagnostic study 1a 1. Anatomical snuff box (ASB) tenderness Sensitivity = 100%<br><br> Specificity = 98% <br><br>PPV = 0.97<br><br>NPV = 1
2. Resisted supination Sensitivity = 100%<br><br>Specificity = 98% <br><br>PPV = 0.97<br><br>NPV = 1
3. Thumb axial compression (AC) Sensitivity = 97.5%<br><br>Specificity = 97.8% <br><br>PPV = 0.95<br><br>NPV = 0.97
A new clinical test for fracture of the scaphoid. Powell JM ,Lloyd GJ, Rintoul RF. 1988, Canada N = 73 Reference standard: Plain radiograph

Diagnostic study 1a
1. New test: pain in ASB during Pronation + Ulnar deviation Sensitivity = 100%<br><br>Specificity = 66% <br><br>PPV = 52<br><br>NPV = 100 Age range not stated.
The scaphoid compression test. Chen SC. 1989, UK N = 52
Reference standard: Plain radiograph
Retrospective study 1. Thumb AC Sensitivity = 70.5%<br><br>Specificity = 91%<br><br>PPV = 0.85<br><br>NPV = 0.70 Retrospective study of 10-year period.
Age range 11-85 yrs.
No break down of results by age group.
Clinical signs in scaphoid fractures. Waizenegger M, Barton NJ, Davis TR, et al. 1994, UK N = 52
Reference standard = Plain or scinitgraphy
Diagnostic study 1a 1. Kirk-Watson test Sensitivity = 82%<br><br>Specificity = 31% Poor description of clinical tests.
Mixture of the reference gold standard test.
2. Clamp test Sensitivity = 26% <br><br>Specificity = 79%
3. ASB tenderness Sensitivity = 87%<br><br>Specificity = 38%
4. Thumb AC Sensitivity = 50%<br><br>Specificity = 51%
5. Pronation and UDev Sensitivity = 83%<br><br>Specificity = 17%
6. Pronation and RDev Sensitivity = 70%<br><br>Specificity = 31%
7. Resisted supination Sensitivity = 83%<br><br>Specificity = 38%
Combining the clinical signs improves diagnosis of scaphoid fractures Parvizi J, Wayman J, Kelly P, et al. 1998, UK N = 215
Reference standard: Plain radiograph
Diagnostic study level 1a 1. ASB tenderness Sensitivity = 100%<br><br>Specificity = 19% <br><br>PPV = 0.3 <br><br>NPV = 1 38 patients lost to follow up.
Age range 6-79 years.
No results breakdown by age.
2. Thumb AC Sensitivity = 100%<br><br>Specificity = 48%<br><br>PPV = 0.4<br><br>NVP = 1
3. Scaphoid tubercle (ST) tenderness Sensitivity = 100%<br><br>Specificity = 30%<br><br>PPV = 0.34 4.<br><br>NPV = 1
4. Loss of thumb ROM Sensitivity - 66% <br><br>Specificity = 66%<br><br>PPV = 0.41 <br><br>NPV = 0.85
5. ASB + AC Sensitivity = 100%<br><br>Specificity = 54%<br><br>PPV = 0.43 <br><br>NVP = 1
6. ASB + AC + ST Sensitivity = 100%<br><br>Specificity = 74%<br><br>PPV = 0.58<br><br>NPV = 1
Examination tests predictive of bone injury in patients with clinically suspected occult scaphoid fracture. Unay K, Gokcon B, Ozkan K et al. 2009, Turkey N = 41 with occult fracture not visible plain film.
Reference standard: MR scans
Diagnostic study 1a 1. Thumb ABD Sensitivity = 73%<br><br>Specificity = 50% <br><br>PPV = 0.86 <br><br>NPV = 0.31 Not stated who performed the clinical tests.
Age range 9-50 years.
Unclear if radiology images were scored independently.
2. Wrist RDev Sensitivity = 68%<br><br>Specificity = 33%<br><br>PPV = 0.93<br><br>NPV = 0.08
3. Thumb AC Sensitivity = 71%<br><br>Specificity = 35%<br><br>PPV = 0.54 <br><br>NPV = 0.54
4. Wrist Flexion Sensitivity = 71%<br><br>Specificity = 50%<br><br>PPV = 0.89<br><br>NPV = 0.23
5. Wrist Extension Sensitivity = 72%<br><br>Specificity = 60%<br><br>PPV = 0.93<br><br>NPV = 0.23
6. Power grip Sensitivity = 67% <br><br>Specificity = 20%<br><br>PPV = 0.86<br><br>NPV = 0.08
7. Wrist UDev Sensitivity = 70% <br><br>Specificity = 36%<br><br>PPV = 0.75<br><br>NPV = 0.31
8. Wrist Pro Sensitivity = 79% <br><br>Specificity = 58%<br><br>PPV = 0.82<br><br>NPV = 0.54
9. Wrist Sup Sensitivity = 76%<br><br>Specificity = 50%<br><br>PPV = 0.79<br><br>NPV = 0.46
10. Pinch grip Sensitivity = 73%<br><br>Specificity = 75%<br><br>PPV = 0.98<br><br>NPV = 0.23
Author Commentary:
Studies vary widely in diagnostic values for a variety of tests. Only one study used MR imaging as the gold standard. There is no consensus as to the best clinical test for a scaphoid fracture.
ASB tenderness in all studies gave 100% sensitivity (i.e. if ASB tenderness is absent, then a fracture is highly unlikely). Specificity ranged from high, at 98% (i.e. if ASB tenderness is present then a fracture is likely) to low, at 19% (i.e. if ASB tenderness is present then a fracture is less likely). There is some evidence that a combination of tests (pain on ASB + AC + ST) will give perfect sensitivity and high specificity.
Most clinical tests had higher sensitivity than specificity, which means that a fracture is unlikely to be missed but they will give a high number of false positives.
Bottom Line:
A combination of clinical tests seems to give the best diagnostic values for a scaphoid fracture.
References:
  1. Waeckerle JF . A prospective study identifying the sensitivity of radiographic findings and the efficacy of clinical findings in carpal navicular fractures.
  2. Powell JM ,Lloyd GJ, Rintoul RF.. A new clinical test for fracture of the scaphoid.
  3. Chen SC.. The scaphoid compression test.
  4. Waizenegger M, Barton NJ, Davis TR, et al.. Clinical signs in scaphoid fractures.
  5. Parvizi J, Wayman J, Kelly P, et al.. Combining the clinical signs improves diagnosis of scaphoid fractures
  6. Unay K, Gokcon B, Ozkan K et al.. Examination tests predictive of bone injury in patients with clinically suspected occult scaphoid fracture.