Use of Sodium Bicarbonate in treatment of lithum toxicity

Date First Published:
November 28, 2005
Last Updated:
February 25, 2009
Report by:
Dr Richard Fawcett, ST 2 EM (University Hospital Aintree)
Three-Part Question:
In [patients with mild to moderate lithium toxicity who are symptomatic thus requiring treatment] is [volume resuscitation with normal saline and sodium bicarbonate or just normal saline alone] better [in improving outcome by enhancing renal elimination of the toxin as well as increasing the alkalinity of urine thus further promoting lithium excretion]