A 50yr old male is 'blue-lighted" into your ED resus in status epilepticus. Despite IV lorazepam and phenytoin, the patient continues to fit and a decision is made to intubate and sedate him, to control his seizures. As the team is preparing to intubate him, you wonder if there is any evidence to support giving him a prophylactic dose of an IV anti-emetic as you are concerned about the potential risks of aspiration and related complications during an RSI?
Do bisphosphonates relieve pain caused by acute osteoporotic vertebral compression fractures? n
A 72-year-old woman presents to the emergency department with severe back pain after a mechanical fall. Plain radiographs of her thoracic spine show osteopenic vertebrae with a wedge compression fracture of the body of T8. Her pain is controlled acutely with paracetamol, ibuprofen and oral morphine sulphate. She is mobilised and arrangements are made for her to have physiotherapy in the community. You are keen to discharge this patient but want to maintain pain control and, given the potential side effects, would prefer to avoid opiates and non-steroidals. You have heard that some bisphosphonates relieve the pain of pathological fractures and wonder whether they do so in vertebral compression fractures.
A patient attends the emergency department (ED) with atraumatic pleuritic chest pain. She is 12 weeks pregnant with no other medical history. A junior doctor has dutifully followed the ED guideline, noted that the patient is at ‘low clinical risk’ of pulmonary embolism (PE) and requested a D-dimer level, which has returned within normal limits. The junior doctor is now keen to discharge the patient, who has remained well in the ED, but wants to ‘run it by you’ first. You are surprised by the normal D-dimer level in pregnancy but wonder whether the sensitivity and negative predictive values are as high in pregnant patients as they are in low risk non-pregnant patients.
Inflatable nasal tampons are less painful than dry hydrophilic nasal tampons
A 45-year-old male presents to the emergency department with active epistaxis. It is determined he will require nasal packing. You have a choice of using a moistened, gel-coated, balloon inflated nasal tampon or a dry hydrophilic nasal tampon, and wonder which is less painful on insertion and removal?
Colchicine as an adjunct to NSAIDs for the treatment of acute pericarditis
A 32-year-old woman with no significant medical history presents to the emergency department with chest pain and dyspnoea. A pericardial friction rub is heard on examination. The ECG shows PR depression and widespread saddle shaped ST elevation. You diagnose acute pericarditis and prescribe a course of non-steroidal anti-inflammatory drugs (NSAIDs). However, recalling that colchicine may be useful for recurrent pericarditis, you wonder whether it is effective for a first episode of acute pericarditis.
You are a Paediatric SpR in a busy DGH and a previously well 6yr old girl is brought into Paediatric resus by ambulance with blood sugar of 32 and a significant acidosis. You make a diagnosis of DKA and commence treatment in accordance with your local Paediatric DKA guideline. However, you notice that the rate of insulin infusion it instructs you to use is 0.1units/kg/hour, which is double that suggested by the South Thames Retrieval Service guideline(1) you had used in your previous hospital. You wonder what the evidence is for the possible benefits of using a lower rate and which is the more appropriate rate to use.
Is montelukast useful in the management of acute bronchiolitis?
It is mid-winter and a 4 month old boy has been admitted to the last bed in our acute admissions ward. He has typical signs and symptoms of moderate bronchiolitis and you wonder if there is a role for oral montelukast in his management.
Congenital Nevocellular Naevi – Do we need to screen with neuroimaging?
A 3 day old neonate female was seen by the neonatologist and noted to have a large congenital melanocytic/nevocellular naevus. The neonate had no focal neurology and was otherwise well in herself following a normal vaginal delivery. There was no family history of note.
Blood gas analysers are typically preset to assume a patient’s temperature is normothermic at 37 degrees centigrade. In clinical practice the temperature of the patient is infrequently taken at the time of sample or entered into the analyser. With emergency departments exposed to patients presenting with temperature extremes, you wonder whether the temperature entered into the gas analyser has a significant effect on results and subsequent clinical management.
A previously health 25 years old man present to the A&E department with a chief complain of vomiting a small amount of fresh blood. You consider doing a risk assessment for outpatient treatment in him, but wonder whether the use of Glasgow-Blatchford risk scoring system is sensitive in recognition the need for admission?
What are the acute withdrawal symptoms in neonates following in utero exposure to stimulant drugs?
The SHO on the post-natal ward is performing routine newborn examinations and notices a baby who is being monitored using a neonatal abstinence score chart due to a history of maternal illicit drug use. Urine toxicology results are positive for amphetamines, but negative for opioids. The SHO has seen the effects of opioid withdrawal on babies before, but asks the SCBU registrar whether babies act in a similar manner when withdrawing from stimulatory drugs such as cocaine and amphetamines.
A 24 year old man presents to the A&E minors department referred by the dental emergency unit. He is complaining of a dull and constant pain localised to the lower right 4th, 5th and 6th. Although he is systemically well you can feel a submandibular swelling just below the affected teeth.
Cylinder plaster versus cricket pad splint in uncomplicated patellar fractures
A 32 year old man presents to the Emergency Department having landed on his knee whilst playing football. His x-ray reveals a closed vertical fracture of his patella. You wonder if a cricket pad splint is as good as a plaster cylinder for immobilisation.
A 34-year-old patient presents to the Emergency Department with altered level of consciousness from a suspected intracranial bleed. The decision is made to intubate him. You predict a difficult airway. As you gather your equipment, you wonder whether use of a new GlideScope device will help achieve better success at intubation as opposed to traditional direct laryngoscopy.
Alpha-blockers increase the chances of a successful trial without catheter
A previously well 60-year-old gentleman attends your Emergency Department in acute urinary retention (AUR) for the past 10 hours. On closer questioning he reveals a history of preceding lower urinary tract symptoms. Following the uneventful passage of a urethral catheter, the production of a residual volume <1000ml and the finding of normal renal function, you wonder whether starting a short course of an alpha-blocker prior to discharge from the Emergency Department may increase his chance of an early trial without catheter (TWOC).