Congenital Nevocellular Naevi – Do we need to screen with neuroimaging?
A 3 day old neonate female was seen by the neonatologist and noted to have a large congenital melanocytic/nevocellular naevus. The neonate had no focal neurology and was otherwise well in herself following a normal vaginal delivery. There was no family history of note.
Blood gas analysers are typically preset to assume a patient’s temperature is normothermic at 37 degrees centigrade. In clinical practice the temperature of the patient is infrequently taken at the time of sample or entered into the analyser. With emergency departments exposed to patients presenting with temperature extremes, you wonder whether the temperature entered into the gas analyser has a significant effect on results and subsequent clinical management.
A previously health 25 years old man present to the A&E department with a chief complain of vomiting a small amount of fresh blood. You consider doing a risk assessment for outpatient treatment in him, but wonder whether the use of Glasgow-Blatchford risk scoring system is sensitive in recognition the need for admission?
What are the acute withdrawal symptoms in neonates following in utero exposure to stimulant drugs?
The SHO on the post-natal ward is performing routine newborn examinations and notices a baby who is being monitored using a neonatal abstinence score chart due to a history of maternal illicit drug use. Urine toxicology results are positive for amphetamines, but negative for opioids. The SHO has seen the effects of opioid withdrawal on babies before, but asks the SCBU registrar whether babies act in a similar manner when withdrawing from stimulatory drugs such as cocaine and amphetamines.
A 24 year old man presents to the A&E minors department referred by the dental emergency unit. He is complaining of a dull and constant pain localised to the lower right 4th, 5th and 6th. Although he is systemically well you can feel a submandibular swelling just below the affected teeth.
The best treatment for partial transection of the thoracic aorta.
An adult patient arrives in the emergency department via ambulance and is unconscious and hypotensive following a car accident in which the patient was wearing a seat-belt. CT with contrast shows a transcection of their thoracic aorta which needs intervention.
Cylinder plaster versus cricket pad splint in uncomplicated patellar fractures
A 32 year old man presents to the Emergency Department having landed on his knee whilst playing football. His x-ray reveals a closed vertical fracture of his patella. You wonder if a cricket pad splint is as good as a plaster cylinder for immobilisation.
A 34-year-old patient presents to the Emergency Department with altered level of consciousness from a suspected intracranial bleed. The decision is made to intubate him. You predict a difficult airway. As you gather your equipment, you wonder whether use of a new GlideScope device will help achieve better success at intubation as opposed to traditional direct laryngoscopy.
Alpha-blockers increase the chances of a successful trial without catheter
A previously well 60-year-old gentleman attends your Emergency Department in acute urinary retention (AUR) for the past 10 hours. On closer questioning he reveals a history of preceding lower urinary tract symptoms. Following the uneventful passage of a urethral catheter, the production of a residual volume <1000ml and the finding of normal renal function, you wonder whether starting a short course of an alpha-blocker prior to discharge from the Emergency Department may increase his chance of an early trial without catheter (TWOC).
Elevation of serum magnesium may improve clinical outcome after aneursymal subarachnoid haemorrhage
A 40 year old female attends the emergency department as a standby call. Her partner gives you a history of acute headache followed by collapse and reduced conscious level. She is rapidly intubated and taken for brain CT, which confirms your suspected diagnosis of acute subarachnoid haemorrhage. The case is discussed with the neurosurgical team on call and transfer is arranged. You are keen to provide prophylaxis against future vasospasm and further brain injury. However, no oral nimodipine is available to go down the NG just inserted. By the time it is sourced the patient will likely have left the department. You are sure you have recently heard about the use of IV magnesium as a further preventative measure for vasospasm in SAH. Serum magnesium is 0.9mmol/L. While you wait for the anaesthetist to facilitate transfer, you resolve to find out for yourself....
A 20 years old gentleman presents with a swollen ankle after an inversion injury. Clinically you suspect a fracture of lower one third of fibula. Radiograph confirms a Weber A fracture which is treated conservatively in a below knee back slab and crutches. You refer him to fracture clinic and very well know that operative fixation is highly unlikely and he will be changed into a full plaster soon. You wonder if giving him low molecular weight heparin might prevent development of deep vein thrombosis.
Timing of antibiotic administration in community-acquired pneumonia
A 70 year-old lady presents to the emergency department(ED) with 2 days of fever, shortness of breath, and cough productive of green sputum. CXR confirms right basal pneumonia. She requires oxygen therapy and admission. It is busy in the ED. This patient has been waiting for 3.5 hours. Her bed is ready in the ward. You wonder if giving her the antibiotics now would affect her clinical outcome in terms of time to clinical stability, length of hospital stay, and mortality.
Nicardipine hydrochloride for hypertensive crisis in patients with aortic dissection
A 55-year-old male patient came to the emergency department with the symptoms of acute onset of severe chest pain with radiation to the back, cold sweating, and nausea. He had mild shortness of breath and his pain was most severe at onset. Physical examination revealed blood pressure: 210/120mmHg, heart rate: 101/min, respiratory rate: 20/min (SpO2 97% at room air), irregular heart beat without murmur, and clear breathing sound over the bilateral lung fields. The electrocardiogram (ECG) revealed atrial fibrillation with rapid ventricular response. Chest computed tomography showed a dissecting aortic aneurysm, from the descending thoracic aorta to the left common and external iliac artery. Therefore, a clinical diagnosis of aortic dissection, Stanford B was made. We wondered whether nicardipine was suitable to control his blood pressure and improve the outcome.
Hypertonic sodium solutions vs mannitol in reducing ICP in traumatic brain injury
A 54 year old female pedestrian has been hit by a bus. She is brought into the ED by ambulance. Her GCS is 13 on arrival and examination reveals an isolated head injury with a haematoma over the left occiput. CT confirms a right frontal contusion with subdural and subarachnoid haemorrhage and a fracture of the left temporal and occipital bones. There is midline shift to the left. On return to the ED, her right pupil appears dilated and her GCS is now 10 (E2M4V4). The neurosurgical registrar is in theatre for the next 20 minutes. You intubate and ventilate the patient and wonder whether hypertonic saline would be better than mannitol at controlling the patient's ICP acutely.
An agitated 24-year-old patient with a history of schizophrenia enters the emergency department, and becomes aggressive and hostile towards staff and patients. De-escalation techniques fail, and the patient will not take oral medication or allow intravenous cannulation. You wonder whether intramuscular (IM) haloperidol or olanzapine is the best drug to rapidly, safely and effectively calm the patient.
A 50 yrs old man presents to the emergency department with central crushing chest pain, sweating and pain radiating to the left shoulder. ECG shows ST elevation in anterior leads. Your hospital is on take for PCI. You have referred him to the cardiology registrar informing that you have initiated the treatment with Aspirin, Clopidogrel and Fragmin. He tells you that he is taking this patient to the angiography suite in the next hour. He enquires if the department has Prasugrel, a new drug and tells you that Prasugrel is better than Clopidogrel for PCI with stent insertion. You wonder what this drug is and how this fares in comparison with Clopidogrel.
